ea0021oc1.4 | Diabetes and metabolism | SFEBES2009
Harte Alison
, Youssef-Elabd Elham
, McGee Kirsty
, Tripathi Gyanendra
, Ashour Esmat
, Aballah Mogha
, Sharada Hayat
, Amin Ashraf
, Ceriello Antonio
, O'Hare Paul
, Kumar Sudhesh
, McTernan Philip
Chronic elevation of saturated fatty acids (SFAs) and glucose (Glc) appears to activate an inflammatory response; compounded by habitual feeding. Restoration of physiological SFAs and Glc levels post-prandially may not attenuate the original insult; a concept termed metabolic memory. Therefore we investigated (1) the effect of chronic and oscillating SFAs and Glc on the inflammatory pathway in human abdominal subcutaneous (AbdSc) adipose tissue (AT) and adipocytes ...